Diagnostics of septic myocardial dysfunction in neonates

Neonatal sepsis (NS) continues to be the one of major problems in neonatal practice. This is due variability clinical manifestations and, part, lack available diagnostic markers that are significantly associated with mortality as a result sepsis. The purpose - study role paraclinical myocardial dysfunction neonates Materials and methods. To achieve this goal, 87 newborns (the main group) generalized infectious-inflammatory process were under our observation. control group included 30 newborns, which infectious inflammatory diseases refuted. Examination treatment patients NS was carried out accordance modern international guidelines recommendations. Results discussion. Based on comprehensive examination group, it found 25 (28.7%) suffered from early sepsis, respectively, remaining 62 (71.3%) had late NS. According severity condition, 76 (87.4%) children required intensive care, provided care unit. average value procalcitonin observation 2.53±0.33 ng/ml, 0.24±0.04 ng/ml (p<0.05). mean values creatine phosphokinase, MB fraction troponin I 58.44±2.39 U/l 0.33±0.05 41.74±2.45 0.04±0.01 Conclusions. Generalized accompanied by increased activity cardiotropic biochemical markers. conducted principles Declaration Helsinki. research protocol approved Local Ethics Committee institution mentioned work. Informed consent children’s parents obtained for research. No conflict interests declared authors.